“We believe these results are applicable to a very broad population”

Focusing on a study of over 6,000 patients, this hugely important piece attempts to finally move forward discussion regarding the long term consequences of deep anaesthesia?

There is no difference in the survival rate of patients who have had a “deep level” of anaesthesia, which is still strictly within the bounds of normal clinical practice. Could this research lead to us using less anaesthesia overall and improving our environmental impact?

The paper being discussed, “Anaesthetic depth and complications after major surgery: an international, randomised controlled trial” is here:


We discuss the RELIEF trial briefly, if you want more on that go here: https://www.topmedtalk.com/ebpom-highlight-1-30-visiting-professor-plenary-lecturer-results-of-the-relief-trial/

We also discuss the work of Dan Sessler, who we interviewed here: https://www.topmedtalk.com/topmedtalks-to-dan-sessler-2/

A fuller look into The Clinical Trials Network is here: https://www.topmedtalk.com/anaesthesia-2019-the-clinical-trials-network-and-optimising-shared-decision-making/

Presented by Desiree Chappell and Monty Mythen with their guests Kate Leslie, Honorary Professor, Monash University, Melbourne, VIC, Australia, Specialist Anaesthetist, The Royal Melbourne Hospital & North Western Mental Health and Non-Executive Director, Australian Medical Council and Timothy Short, Clinical Anaesthetist and Honorary Professor at Auckland University Hospital, New Zealand.