Andy Cumpstey and Mike Grocott interview Kate Leslie about the SNaPP study (Sugammadex, Neostigmine, and Postoperative Pulmonary Complications). SNaPP is a pragmatic randomized study run from the University of Melbourne with the ANZCA Clinical Trials Network across 45 sites in Australia, New Zealand, and Hong Kong. Patients aged 40+ having major abdominal or thoracic surgery (≥2 hours, overnight stay) were randomized after induction to reversal with sugammadex or neostigmine, with anesthetists unblinded and encouraged to use quantitative neuromuscular monitoring. In this podcast Andy, Mike and Kate discuss the results and their implications for anaesthetists and healthcare systems.
Find the paper here: https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(26)00158-X/fulltext
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