The effectiveness and cost-effectiveness of INSPIRatory musclE training (IMT) for reducing postoperative pulmonary complications (PPC): a sham-controlled randomised controlled trial (RCT) (INSPIRE). This piece is a concise guide to the method and thinking behind the trial.

Presented by Denny Levett, Professor in Perioperative Medicine and Critical Care at the University of Southampton, Consultant in Perioperative Medicine, Southampton University Hospital NHS Foundation trust (UHS), President, Perioperative Exercise Testing and Training Society (POETTS) and biannual chair of the National Perioperative Cardiopulmonary Exercise Testing course, she’s also part of the Fit 4 Surgery research group in Southampton, investigating exercise and nutritional optimisation before major surgery and is clinical CI for the multi-centre INSPIRE trial.